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Signs and symptoms of liver derived renal injury

Dec 29, 2016
History and symptoms
(a) of hepatitis B virus associated glomerulonephritis in children and male, hepatitis B or hepatitis B virus, the clinical manifestations of asymptomatic proteinuria or nephrotic syndrome, a few patients had hematuria.
(two) liver cirrhosis glomerulonephritis in cirrhotic patients, showed abnormal urine (such as hematuria), hypertension and renal insufficiency, few patients have no clinical manifestations, deterioration of renal function is relatively slow.
(three) hepatorenal syndrome is common in decompensated hepatic dysfunction, most patients have certain incentives, such as excessive diuresis, large volume paracentesis, gastrointestinal bleeding and application of some nephrotoxic drugs; usually in the serious damage of liver function at the same time or after oliguria, in a few days, weeks or number
Within a month of the deterioration of renal function, often accompanied by nausea, vomiting, mental apathy and lethargy; severe cases with hepatic encephalopathy and coma, infection, hemorrhage, hypotension and liver failure is the main cause of death of patients.
Two, physical examination found
Hepatic disease, jaundice, spider, liver palms, splenomegaly, ascites, edema of lower limbs or eyelids.
Three, auxiliary examination
(a) positive serum HBV antigen and positive HBV antigen in renal slices are evidence of hepatitis B virus associated glomerulonephritis.
(two) cirrhotic glomerulonephritis, urine changes with increased proteinuria proliferative lesions, cylindruria and hematuria became obvious, but gross hematuria than primary IgA nephropathy is rare, most of the patients blood circulating immune complexes positive blood, immune globulin increased, especially IgA increased
Prominent, a small number of patients with decreased blood C3.
(three) hepatorenal syndrome in patients with urinary protein negative or normal urine trace, or a small amount of red, white cells and tube; thrombocytopenia, anemia and abnormal liver function; Ccr decreased significantly, blood urea nitrogen, creatinine.
(four) B ultrasound examination can have the change of cirrhosis, but there is no change in the kidney.

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