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Understand the symptoms of diabetic nephropathy to avoid disease progression

Oct 09, 2017

Diabetic nephropathy is a chronic kidney complication caused by diabetes, once the obvious symptoms of diabetic nephropathy, have entered a later stage, the treatment of diabetic nephropathy brought great difficulty, according to the progress of diabetic nephropathy, diabetic nephropathy Symptoms are different:

Proteinuria: Proteinuria is the first sign of diabetic nephropathy. Diabetic nephropathy early, urine only a small amount of albumin symptoms, selective proteinuria, this state can last for many years. With the progress of diabetic nephropathy, patients began to appear persistent proteinuria symptoms, glomerular filtration rate gradually decreased, the severity of kidney disease will be further aggravated. At this point, patients with diabetic nephropathy in a large number of proteinuria, glomerular filtration rate is lower than normal, the patient's progress in the deterioration of the kidneys will be difficult to control, and soon will develop into diabetic renal failure.

Edema and nephrotic syndrome: early diabetic nephropathy patients generally no swelling; when diabetic patients with 24-hour urine protein quantification of more than 3 grams, the swelling will appear. Once the patient has obvious systemic swelling, the condition of diabetic nephropathy continued to progress. Diabetic nephropathy patients with physical edema symptoms more than half of the affected population, which may be due to diabetic patients suffering from kidney disease caused by a large number of protein caused by hypoproteinemia. Diabetic nephropathy longer course of disease, causing edema of diabetic nephropathy more complications, of which about 20% of diabetic patients with nephrotic syndrome.

Hypertension: Hypertension is common in patients with diabetic nephropathy, which is a late symptom of diabetic nephropathy and occurs in patients with diabetic nephropathy with longer duration of persistent proteinuria. In the early stage, patients with diabetic nephropathy only increase blood pressure after exercise; when persistent proteinuria occurs, blood pressure continues to increase. The emergence of high blood pressure will accelerate the progress of renal function in patients with diabetic nephropathy, so effective control of hypertension in patients with diabetic nephropathy is very important.

Renal failure: Once the kidney has kidney damage, the course of the disease is progressive, and eventually develop into azotemia, uremia. Early stage of diabetic nephropathy, in order to adapt to the needs of the body's sugar, glomerular filtration rate increased blood urea nitrogen and creatinine levels normal. Once the body of persistent proteinuria, the patient's blood urea nitrogen and creatinine concentration will increase, resulting in renal dysfunction, this time not to control, diabetic nephropathy in more than a few years to develop uremia.

Anemia: patients with significant azotemia in diabetic nephropathy, may have mild to moderate anemia symptoms, with iron therapy is invalid. Anemia is caused by erythropoiesis, which may be associated with long-term restrictions on protein diets and azotemia in patients with diabetic nephropathy.

Understand the symptoms of diabetic nephropathy to avoid disease progression

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