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Prognosis of nephrotic syndrome

Dec 26, 2016
The prognosis of nephrotic syndrome varies greatly. The main prognostic factors included: (1) pathological type. In general, the prognosis of minimal change nephropathy and mild mesangial proliferative glomerulonephritis is good. Some patients with minimal change nephropathy can spontaneous remission, remission rate is high, but ease relapse after remission. Early membranous nephropathy still has a higher treatment remission rate, although late stage is difficult to achieve remission, but most of the progress is slow, renal failure occurs late. Mesangial capillary glomerulonephritis and severe mesangial proliferative glomerulonephritis have poor efficacy, poor prognosis, rapid access to chronic renal failure. The main influencing factors of focal segmental glomerulosclerosis is the prognosis of urinary protein and the degree of response to treatment, natural history in patients with nephrotic syndrome kidney 10 years survival rate was 90%, and 50% for nephrotic syndrome; nephrotic syndrome of hormone therapy in remission 10 year graft survival rate is above 90%, invalid only 40% of them. (2) clinical factors. A large number of proteinuria, hypertension and hyperlipidemia can promote glomerular sclerosis, these factors such as long-term control can not be, become an important factor in poor prognosis. (3) recurrent infection and thromboembolic complications often affect prognosis.

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