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What is the cause of hyponatremia in nephrotic syndrome

Dec 27, 2016
Patients with nephrotic syndrome will have hyponatremia, clinical thought nephrotic syndrome patients, serum sodium 120mmol/L belongs to hyponatremia. Nephrotic syndrome hyponatremia has the following reasons:

1 long term use of adrenal cortical hormone treatment of nephrotic syndrome, so that adrenal cortical function is inhibited, once the use of corticosteroids, secondary cortical dysfunction occurs.
2 long-term low salt or salt free diet leads to the body of salt.
3 bad appetite and vomiting, diarrhea not only makes the source of sodium deficiency, and loss of potassium and sodium salts from the gastrointestinal tract.
4 diuretics caused by loss of sodium and potassium.
5 in the case of low sodium and the input of a number of electrolyte free solution can lead to hyponatremia hyponatremia, combined with increased secretion of antidiuretic hormone, renal tubular heavier intake of sodium and water can cause dilution hyponatremia.
If hyponatremia and hyponatremia exist simultaneously in patients with nephrotic syndrome, serum sodium will fall even lower, even 115mmol/L. When the serum sodium is too fast, even in the serum sodium 120mmol/L, patients can also occur convulsions, hypotension and plasma bicarbonate with reduced ventilation caused by secondary respiratory alkalosis. But if the serum sodium slowly decreased, of course, 115mmol/L, but also no obvious clinical symptoms.

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