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What are the side effects of hormone therapy for nephrotic s

Dec 28, 2016
Nephrotic syndrome is a clinical syndrome characterized by massive proteinuria, hypoproteinemia and hyperlipidemia. At present, the treatment of nephrotic syndrome is mostly treated with glucocorticoid. However, the long-term use of hormones will have side effects, so many patients have resistance to hormone therapy, often self stopping hormones, resulting in a serious recurrence of the disease. The comprehensive treatment of kidney disease in western medicine is the use of hormones, hormone called "glucocorticoid", the normal is secreted by the adrenal cortex. Hormone drugs including prednisone, prednisolone and dexamethasone, anti-inflammatory, anti allergy and immune function, some of the primary or secondary glomerular diseases, with a diuretic, reduce protein and protect renal function and urinary function. Therefore, clinical minimal change disease, mild to moderate mesangial proliferative nephritis, membranous nephropathy, early proliferative lupus nephritis and other pathological types caused by nephrotic syndrome is the most commonly used this method of treatment. Western medicine hormones, immunosuppressive drugs for the treatment of nephrotic syndrome can achieve rapid elimination of symptoms of treatment, but there are also a large number of side effects are not conducive to the body, the disease recurrence and other drawbacks. While the traditional Chinese medicine treatment of nephrotic syndrome can fundamentally repair the damage of renal function, but because of slow effect, many patients are difficult to adhere to the correct. Therefore, in the face of different treatment methods of nephrotic syndrome, patients need to weigh, to choose the best treatment, to achieve the best treatment effect is appropriate. Although there are many side effects of hormones, but the most important is the following: 1, affecting the growth and development of children: hormones can inhibit the growth hormone production, thereby affecting the growth and development of children. 2, immune function decline: induced or aggravated infection, infection, in turn, aggravate the kidney, forming a vicious cycle. 3, can cause gastric ulcer, or aggravating stomach trouble, cause gastric bleeding. 4, metabolic disorders: pided into fat metabolism disorders and sugar metabolism disorders and calcium and phosphorus metabolism disorders. Fat metabolism disorder of the moon face, buffalo back to central obesity; glucose metabolic disorder of some patients can cause hyperglycemia and diabetes are therefore used with caution; metabolism of calcium and phosphorus for osteoporosis, avascular necrosis of the femoral head. Reminder: the long-term use of hormone therapy can lead to adrenal cortical atrophy, if a sudden reduction or sudden withdrawal, can cause the body's response to stress, because of lack of hormone induced adrenal crisis, fever (temperatures above 40 degrees Celsius), nausea, vomiting, decreased blood pressure, shock can be serious, so the patient is not free to stop.

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