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Complications and treatment of nephrotic syndrome

Dec 31, 2016
1 infection: select an effective, nephrotoxic antibiotic, given adequate doses and adequate treatment to control infection.
2 low volume shock: timely treatment, intravenous infusion of low molecular dextran, physiological saline, isotonic fluid. When necessary to give intravenous hydrocortisone. 3 hypercoagulable state and thromboembolic complications: hypercoagulable state is a common complication of nephrotic syndrome, renal vein thrombosis can lead to renal failure, should be promptly given anticoagulant therapy. Prothrombin time, fibrinogen and platelet count were monitored during treatment. Anticoagulant therapy includes:
1):: 100u/kg.d, anticoagulant heparin dissolved in saline or 10% 100ml glucose, 2 hour intravenous infusion, medication during the monitoring of prothrombin time. Low molecular weight heparin: 80u/kg, subcutaneous injection, side effects, is now widely used in clinical.
2) fibrinolytic drugs:
Urokinase: the first dose of 40000u dissolved in 10% glucose or saline 100ml intravenous drip, and later changed to 20000u/d maintenance, during the monitoring of fibrinogen.
Baoshenkang: dose 10-15mg/kg.d..
3) platelet antagonists: Pan Shengding: 3mg/kg.d, (the most "150mg/d" 2~3, oral. Aspirin: 5~10mg/kg. 4 renal tubular dysfunction: pay attention to timely correction of water, electrolyte and acid-base imbalance, to avoid the use of nephrotoxic drugs.
5 protein calorie malnutrition: lack of a reasonable diet, containing high quality protein foods, and supplement of trace elements, vitamin D and calcium.
6 endocrine disorders: hypothyroidism, growth disorders, renal osteodystrophy, detection of thyroid hormone, growth hormone, take appropriate treatment.

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