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What are the symptoms of early nephrotic syndrome

Dec 31, 2016
With the development of society, people's work and life pressure is also growing. And many young people suffer from kidney disease. Nephrotic syndrome has become a common kidney disease, many patients with nephrotic syndrome is because they don't understand the symptoms of nephrotic syndrome and delayed treatment of nephrotic syndrome, so what are the symptoms? Here we take a look at what are the symptoms of nephrotic syndrome.

The main symptoms of nephrotic syndrome:
1, a large number of proteinuria: a large number of proteinuria is a sign of nephrotic syndrome. Glomerular filtration rate, plasma protein concentration and protein intake directly affect the degree of proteinuria. Reduced glomerular filtration rate, proteinuria will reduce; severe hypoproteinemia, urinary protein excretion increased, high protein diet will increase the excretion of urinary protein, therefore, only to every protein, can not accurately judge the degree of proteinuria, but further albumin clearance rate, urinary protein / creatinine (>3.5 often nephrotic range proteinuria).
2, patients with edema: most noticeable symptoms are progressive systemic edema, initial morning eyelid, face and ankle edema; with the progression of the disease and systemic edema, ascites, pleural effusion, pericardial effusion, mediastinal effusion, edema of scrotum or labia, also can appear pulmonary edema. Serious person can't open eyes, head and neck skin is thick, waxy pallor, and chest, ascites, so obvious breathing difficulties, not only sitting supine. If there is skin damage, the tissue fluid overflow and not easy to stop.
3, hypoproteinemia: nephrotic syndrome is an essential feature of the second. Serum albumin was lower than 30g/L. Nephrotic syndrome increased synthesis of albumin in liver syndrome, when given enough protein and calories in the diet, the liver synthesis of albumin in patients with about 22.6g per day, significantly increased than normal 15.6g every day. When the compensatory effect of albumin is not enough to make up for the loss of urine protein, it will appear hypoproteinemia. There was no consistent relationship between hypoproteinemia and urinary protein excretion.
4, hyperlipidemia: the total cholesterol, the level of triglyceride increased significantly, low density lipoprotein (LDH), very low density lipoprotein (VLDH) levels increased in this disease, and the level of serum lipid and the level of. Hyperlipidemia is associated with hypoalbuminemia, LDL/HLDL is only increased when serum albumin is below 10 ~ 20g/L. High density lipoprotein (HDL) normal or decreased. The increased LDL/HDL ratio may increase the risk of atherosclerosis, which is associated with thrombosis and progressive glomerulosclerosis.
These are the symptoms of nephrotic syndrome, through the introduction of the above believe that you have a certain understanding of the symptoms of nephrotic syndrome. If the above symptoms, but also to be vigilant, early treatment.

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