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Expert analysis of treatment of nephrotic syndrome

Dec 31, 2016
Nephrotic syndrome is a group of syndrome, which is caused by a variety of causes, such as stool proteinuria, edema, hyperlipidemia and so on. If you can check the diagnosis in time, can be effectively treated.
First, the general treatment: there are severe edema and low blood pressure should be bed rest, low salt (2-3g/) diet, control of water intake; and given a high protein diet, adult daily 60 - 80g.
Two, edema treatment: mild edema nephritis patients without treatment, the limit salt and rest can disappear. Obvious edema patients, can be used for drug treatment, general intermittent application is better than continuous application.
Three, bed rest: bed rest is very important. Acute nephritis edema, decreased blood pressure, abnormal urine after the loss, the amount of patients can walk, gradually increase the number of mild activities, but do not suddenly increase the amount of activity.
Four, anti infection treatment: in the acute phase of patients with nephritis in the case of infection should be given adequate anti infection treatment, no infection, generally do not have to properly.
Five, diuretic swelling: under normal circumstances, 1 weeks of treatment in the application of adrenal hormones, urine volume will increase quickly, without the use of diuretics. The effect of hormone, edema cannot abate or reduce the amount of urine, can give Dihydrochlorothiazide 25-50mg, 3 times daily, karron body Shutong 20 40mg, 3 times a day; or determination of 50 100mg, 3 times a day, the effect is not significant when using furosemide or ethacrynic acid combined with Paul potassium diuretic dosage may be the first volume of conventional start. For intractable renal edema, dopamine 20mg, 10mg phentolamine plus 10% glucose solution 250ml, or low molecular dextran 500ml, intravenous furosemide 40 60mg, intravenous injection, 1 times a day, a total of 2 - 5 times, often can get good results.
In six, hypertension and heart failure: the presence of hypertension nephritis patients need routine treatment of hypertensive heart failure. The patients with acute nephritis, nephritis patients early problems of high blood volume, emphasis should be placed in the treatment of clear water and sodium retention, reduce blood volume. Water intake to urine, edema, hypertension there is no comprehensive and degree of heart failure to determine, in acute nephritis patients with limited water is appropriate, but not excessive salt intake. In case of edema and hypertension, can be limited to about 2g/d. The intake of protein, as the index limit, with high quality protein protein is preferred, such as eggs, milk, lean meat, etc.. Generally advocated into the low protein, high sugar diet continued until the onset of diuretic, nephritis patients to be able to relieve the symptoms of the basic, can restore the regular diet.
Seven, glucocorticoid hormone: prednisone, prednisolone, hydrogen fluoride prednisolone and dexamethasone. From small to large doses, dosage, course of treatment and withdrawal indications were not consistent. Type I primary nephrotic syndrome, a part of the natural remission can be achieved, and the efficacy of type. Long term hormone treatment, attention should be paid to the side effects of hormones. Intermittent treatment of side effects, can be used for long-term maintenance treatment. There are more chances of infection when using hormone therapy, so it is necessary to strengthen the anti infective therapy.

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