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Relationship between proteinuria and edema

Dec 21, 2017

Proteinuria and edema are the clinical manifestations of renal disease, colds, exertion and other factors will affect the kidney disease in patients with renal barrier filtration barriers, resulting in a large number of proteinuria. The formation of proteinuria often lead to edema, then what is the relationship between proteinuria and edema?

Relationship between proteinuria and edema

The formation of proteinuria reduces the body's effective blood volume

Nephropathy occurs in patients with proteinuria, the body hypoproteinemia, the water in the plasma will shift. Therefore, the water leakage of blood, the patient's effective blood volume will be greatly reduced. Upon receiving a signal of hypovolemia, the human brain activates the renin-angiotensin-aldosterone system in the patient's body, resulting in an increase in renal tubular reabsorption of sodium and water. On the other hand, the signal sent will make the kidneys reduce sodium excretion. Under the joint action of both sides, a large amount of sodium and water retention in patients with kidney disease eventually lead to edema in the body.

Proteinuria leads to hypoalbuminemia, resulting in a decrease in the patient's plasma colloid osmotic pressure

Once kidney disease is found, the protein content of the patient's blood will be continuously excreted in the urine through the injured kidneys. Body lost a large number of proteins, the body is in negative nitrogen balance, the formation of hypoproteinemia. Hypoproteinemia will lead to decreased plasma colloid osmotic pressure in patients with nephropathy, so that the blood vessels within the renal disease patients will move to the hypertonic interstitial fluid, resulting in edema.

The above is the introduction of the relationship between proteinuria and edema, hoping to help patients with kidney disease, once such symptoms occur, we must early detection and early treatment, but also to find highly specialized hospitals and experts to accurately diagnose and avoid Misdiagnosis and mistreatment.

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