Best Hospital for Kidney Disease

Email   Call Us:0086-15176446195

Why does uremia patient produce muscle convulsion?

Dec 30, 2016
Muscle spasm is a common symptom in uremic patients. Cause tic reason is more complex, but the common cause of the abnormal calcium or uremia. Calcium is a kind of electrolyte which is closely related to the excitability of nerve and muscle in vivo. When calcium ion decreases, neuromuscular excitability increased, can cause muscle twitching. While hypocalcemia is common in patients with uremia, and often associated with hyperphosphatemia. The kidney is the main organ for the synthesis of active vitamin D, the role of vitamin D is to regulate the metabolism of calcium and phosphorus, maintain the product of calcium and phosphorus in a certain range. In patients with uremia due to kidney activity lack of vitamin D, calcium and phosphorus balance of body is broken, reduce the intestinal absorption of calcium, phosphorus excretion decreased, decreased blood calcium, blood phosphorus. Some diuretic furosemide (Lasix) will increase the excretion of calcium. Occasionally patients due to intravenous bicarbonate acidosis, low calcium induced convulsions, this is because in a relatively acidic environment, will increase the concentration of free calcium, once the acidosis was corrected, the concentration of free calcium ion can be reduced, resulting in muscle twitching.
In addition to calcium abnormalities in patients with uremia, due to uremic toxins, can also occur in uremic peripheral neuropathy, can cause muscle twitching. In addition, patients with uremia due to metabolic disorders, can be associated with restless leg syndrome, manifested as limb spasms and involuntary activities, need to constantly exercise to feel comfortable, which is part of patients with muscle twitch.

Contact the Health Information Center

Phone: 0086-15176446195 | TTY: 0086-15176446195 | Email: | Hours: 8:00 a.m. to 22:00 p.m. China time