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Nephrotic syndrome diagnosis should know!

Nov 23, 2017

As more and more diseases around us, we are getting less and less understanding of the disease, nephrotic syndrome, which is a disease that many people have never heard of, simply to explain that nephrotic syndrome is a small kidney Increased permeability of the basement membrane with glomerular filtration rate and other glomerular lesions such as a group based syndrome, so how to check it nephrotic syndrome, the following for everyone to introduce.

Nephrotic syndrome diagnosis should know!

A large number of proteinuria is the most important clinical manifestations of NS patients, but also the most basic pathophysiology of nephrotic syndrome. Large amounts of proteinuria refers to adult urinary protein excretion> 3.5g / d. Under normal physiological conditions, the glomerular filtration membrane has a molecular barrier and a charge barrier, resulting in an increase in the protein content of the original urine, forming a large amount of proteinuria when it far exceeds the absorption capacity of the proximal convoluted tubule. On this basis, urinary protein excretion can be exacerbated by any factor that increases the pressure inside the glomeruli and causes hyperperfusion and hyperfiltration (such as high blood pressure, high protein diet or heavy infusion of plasma proteins).

Nephrotic syndrome diagnosis steps are:

First of all, to diagnose whether nephrotic syndrome;

Then, to diagnose whether it is primary nephrotic syndrome;

Second, it needs to be differentiated from the systemic nephrotic syndrome and congenital hereditary diseases;

Finally, to know what kind of glomerular disease caused by renal biopsy must be confirmed.

In fact, different situations, have different symptoms, which is the diagnosis of nephrotic syndrome:

1, systemic lupus nephritis

Occur in middle-aged women and adolescents, immunological examination revealed a variety of autoantibodies, and multiple system damage, can confirm the diagnosis.

2, allergic purpura nephritis

Occur in adolescents, a typical skin purpura, often symmetrical distribution of the distal limbs, more than 1 to 4 weeks after the rash hematuria and (or) proteinuria.

3, Hepatitis B virus-associated nephritis

More common in children and adolescents, clinical manifestations of proteinuria or NS, the common pathological type membranous nephropathy. Diagnostic basis: ① serum HBV antigen positive; ② suffering from glomerulonephritis, and exclude secondary glomerulonephritis; ③ kidney biopsy to find HBV antigen.

The above is the relevant information collected by experts, surely we have some understanding of the above common sense it! Only the correct diagnosis, to better treatment. If you have other kidney problems can browse other pages, you can also give us a message, with the nephrology expert Tongshan Church Chinese medicine hospital will give you the most professional and most effective treatment or advice.

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